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المرصد الرياضية

خبر طبي سار .. أمريكا تسمح بأول علاج لمرض الكبد الدهني الحاد وتكشف موعد طرحه بالصيدليات

خبر طبي سار .. أمريكا تسمح بأول علاج لمرض الكبد الدهني الحاد وتكشف موعد طرحه بالصيدليات
1 سنة 7 1
صحيفة المرصد: أجازت السلطات الصحية الأميركية، الخميس، أول علاج لمرض الكبد الدهني البشري الحاد.

وبات مسموحاً منح هذا العلاج الذي طوّرته شركة "مادريغال" للأدوية، للبالغين المصابين بالتهاب الكبد الدهني غير الكحولي (NASH) والذين يعانون من تليف الكبد.

ويرتبط هذا المرض ارتباطا وثيقا بالبدانة، ويمثل سوقا ضخمة لمجموعات الأدوية.

واعتبرت "مؤسسة الكبد الأميركية" في بيان أن قرار وكالة الأغذية والأدوية الأميركية "إف دي آيه" "يجلب الأمل لملايين الأميركيين".
​​​

ويؤخذ العلاج عن طريق الفم مرة واحدة يومياً، بالإضافة إلى اتباع نظام غذائي سليم وممارسة الرياضة.

وكانت الآثار الجانبية الأكثر شيوعا هي الإسهال والغثيان.

وقالت الشركة إن العلاج سيكون متاحا للمرضى في الولايات المتحدة اعتبارا من أبريل من خلال صيدليات متخصصة.
التعليقات (7)

التعليقات مغلقة

MessagesRequestTimelineExceptionsViews9Queries19Models6Livewire0MailsGate
SettingsRequest history226msRequest Duration47MBMemory Usage10.x
Laravel Version
10.48.28
PHP Version
8.1.33
Environment
production
Debug Mode
Enabled
URL
new.al-marsd.com
Timezone
Asia/Riyadh
Locale
ar
GET article/{id}/{section_title?}/{title?}/{comment_id?}
status
200 OK
full_url
https://new.al-marsd.com/article/192308/%D8%B5%D8%AD%D8%A9/%D8%AE%D8%A8%D8%B1-%D8%B7%D8%A8%D9%8A-%D8...
action_name
article.show
controller_action
App\Http\Controllers\Web\ArticleController@show
Theme
Open Button Position
Hide Empty Tabs
Autoshow
Reset to defaults
    status
    200 OK
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    https://new.al-marsd.com/article/192308/%D8%B5%D8%AD%D8%A9/%D8%AE%D8%A8%D8%B1-%D8%B7%D8%A8%D9%8A-%D8...
    action_name
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    App\Http\Controllers\Web\ArticleController@show
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    GET article/{id}/{section_title?}/{title?}/{comment_id?}
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    controller
    App\Http\Controllers\Web\ArticleController@show
    file
    app/Http/Controllers/Web/ArticleController.php:37-77
    middleware
    web
    telescope
    View in Telescope
    duration
    227ms
    peak_memory
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    []
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    array:23 [▼
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    0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7"
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    • Booting (108ms)time
    • Application (118ms)time
    • Routing (2.6ms)
    • Preparing Response (74.3ms)
    • View: web.singleviews
    • View: web.components.structured-dataviews
    • View: web.components.dateviews
    • View: web.components.social-sharingviews
    • View: components.smart-ad-componentviews
    • View: components.smart-ad-componentviews
    • View: web.layouts.masterviews
    • View: web.layouts.headerviews
    • View: web.layouts.footerviews
    • 1 x Application (52.11%)
      118ms
      1 x Booting (47.89%)
      108ms
      1 x Preparing Response (32.81%)
      74.30ms
      1 x Routing (1.15%)
      2.60ms
      9 x View (0%)
      0μs
      9 templates were rendered
      • web.singlesingle.blade.php#?blade
      • web.components.structured-datastructured-data.blade.php#?blade
      • web.components.datedate.blade.php#?blade
      • web.components.social-sharingsocial-sharing.blade.php#?blade
      • components.smart-ad-componentsmart-ad-component.blade.php#?blade
      • components.smart-ad-componentsmart-ad-component.blade.php#?blade
      • web.layouts.mastermaster.blade.php#?blade
      • web.layouts.headerheader.blade.php#?blade
      • web.layouts.footerfooter.blade.php#?blade
      19 statements were executed (4 duplicates)Show only duplicatesnew_mainnew_comments16.96ms
      • ArticleController.php#40new_mainConnection Established
        Backtrace
        • app/Http/Controllers/Web/ArticleController.php:40
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • ArticleController.php#40new_main1.77msselect * from `articles` where `status` = 1 and `articles`.`id` = '192308' and `articles`.`deleted_at` is null limit 1
        Bindings
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        • 1: 192308
        Backtrace
        • app/Http/Controllers/Web/ArticleController.php:40
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • ArticleController.php#40new_main600μsselect `sections`.*, `article_section`.`article_id` as `pivot_article_id`, `article_section`.`section_id` as `pivot_section_id` from `sections` inner join `article_section` on `sections`.`id` = `article_section`.`section_id` where `article_section`.`article_id` in (192308) and `sections`.`deleted_at` is null
        Backtrace
        • app/Http/Controllers/Web/ArticleController.php:40
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:205
      • ArticleController.php#81new_commentsConnection Established
        Backtrace
        • app/Http/Controllers/Web/ArticleController.php:81
        • app/Http/Controllers/Web/ArticleController.php:74
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • ArticleController.php#84new_comments2.03msselect count(*) as aggregate from `comments` where `status` in (1, 2) and `article_id` = '192308' and `type` = 1 and `comments`.`deleted_at` is null
        Bindings
        • 0: 1
        • 1: 2
        • 2: 192308
        • 3: 1
        Backtrace
        • app/Http/Controllers/Web/ArticleController.php:84
        • app/Http/Controllers/Web/ArticleController.php:74
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • ArticleController.php#89new_comments5.79msselect count(*) as aggregate from `comments_archive` where `status` in (1, 2) and `article_id` = '192308' and `type` = 1
        Bindings
        • 0: 1
        • 1: 2
        • 2: 192308
        • 3: 1
        Backtrace
        • app/Http/Controllers/Web/ArticleController.php:89
        • app/Http/Controllers/Web/ArticleController.php:74
        • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
        • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
        • vendor/laravel/framework/src/Illuminate/Routing/Route.php:260
      • single.blade.php#10new_main490μsselect * from `authors` where `authors`.`id` = 0 and `authors`.`deleted_at` is null limit 1
        Bindings
        • 0: 0
        Backtrace
        • view::web.single:10
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • helpers.php#424new_comments1.27msselect count(*) as aggregate from `comments` where `status` in (1, 2) and `article_id` = 192308 and `comment_id` is null and `type` = 1 and `comments`.`deleted_at` is null
        Bindings
        • 0: 1
        • 1: 2
        • 2: 192308
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        Backtrace
        • app/Helpers/helpers.php:424
        • app/Helpers/helpers.php:435
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
      • helpers.php#430new_comments870μsselect count(*) as aggregate from `comments_archive` where `status` in (1, 2) and `article_id` = 192308 and `type` = 1 and `comment_id` is null
        Bindings
        • 0: 1
        • 1: 2
        • 2: 192308
        • 3: 1
        Backtrace
        • app/Helpers/helpers.php:430
        • app/Helpers/helpers.php:435
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
      • helpers.php#308new_main1.26msselect * from `smart_ads` where `slug` = '6th-MPU-Single-Desktop' limit 1
        Bindings
        • 0: 6th-MPU-Single-Desktop
        Backtrace
        • app/Helpers/helpers.php:308
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • SmartAdComponent.php#34new_main280μsselect * from `smart_ads` where `slug` = '6th-MPU-Single-Desktop' limit 1
        Bindings
        • 0: 6th-MPU-Single-Desktop
        Backtrace
        • app/View/Components/SmartAdComponent.php:34
        • vendor/laravel/framework/src/Illuminate/View/Component.php:135
        • view::web.single:278
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • helpers.php#308new_main280μsselect * from `smart_ads` where `slug` = '1st-MPU-Desktop' limit 1
        Bindings
        • 0: 1st-MPU-Desktop
        Backtrace
        • app/Helpers/helpers.php:308
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • SmartAdComponent.php#34new_main240μsselect * from `smart_ads` where `slug` = '1st-MPU-Desktop' limit 1
        Bindings
        • 0: 1st-MPU-Desktop
        Backtrace
        • app/View/Components/SmartAdComponent.php:34
        • vendor/laravel/framework/src/Illuminate/View/Component.php:135
        • view::web.single:680
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • helpers.php#308new_main250μsselect * from `smart_ads` where `slug` = '4th-MPU-Desktop' limit 1
        Bindings
        • 0: 4th-MPU-Desktop
        Backtrace
        • app/Helpers/helpers.php:308
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • helpers.php#308new_main260μsselect * from `smart_ads` where `slug` = '5th-MPU-Desktop' limit 1
        Bindings
        • 0: 5th-MPU-Desktop
        Backtrace
        • app/Helpers/helpers.php:308
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • header.blade.php#119new_main310μsselect * from `settings` where `name` = 'nasher_header_text_font_size' limit 1
        Bindings
        • 0: nasher_header_text_font_size
        Backtrace
        • view::web.layouts.header:119
        • vendor/laravel/framework/src/Illuminate/Cache/Repository.php:396
        • vendor/laravel/framework/src/Illuminate/Cache/CacheManager.php:429
        • view::web.layouts.header:120
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • header.blade.php#122new_main220μsselect * from `settings` where `name` = 'nasher_header_text_color' limit 1
        Bindings
        • 0: nasher_header_text_color
        Backtrace
        • view::web.layouts.header:122
        • vendor/laravel/framework/src/Illuminate/Cache/Repository.php:396
        • vendor/laravel/framework/src/Illuminate/Cache/CacheManager.php:429
        • view::web.layouts.header:123
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • footer.blade.php#29new_main250μsselect * from `settings` where `name` = 'nasher_footer_text_font_size' limit 1
        Bindings
        • 0: nasher_footer_text_font_size
        Backtrace
        • view::web.layouts.footer:29
        • vendor/laravel/framework/src/Illuminate/Cache/Repository.php:396
        • vendor/laravel/framework/src/Illuminate/Cache/CacheManager.php:429
        • view::web.layouts.footer:30
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • footer.blade.php#32new_main240μsselect * from `settings` where `name` = 'nasher_footer_text_color' limit 1
        Bindings
        • 0: nasher_footer_text_color
        Backtrace
        • view::web.layouts.footer:32
        • vendor/laravel/framework/src/Illuminate/Cache/Repository.php:396
        • vendor/laravel/framework/src/Illuminate/Cache/CacheManager.php:429
        • view::web.layouts.footer:33
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • helpers.php#308new_main310μsselect * from `smart_ads` where `slug` = '7th-MPU-Desktop' limit 1
        Bindings
        • 0: 7th-MPU-Desktop
        Backtrace
        • app/Helpers/helpers.php:308
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      • helpers.php#308new_main240μsselect * from `smart_ads` where `slug` = '7th-MPU-Desktop-Sport' limit 1
        Bindings
        • 0: 7th-MPU-Desktop-Sport
        Backtrace
        • app/Helpers/helpers.php:308
        • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
        • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
        • vendor/livewire/livewire/src/ComponentConcerns/RendersLivewireComponents.php:69
        • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
      App\Models\SmartAd
      4SmartAd.php#?
      App\Models\Article
      1Article.php#?
      App\Models\Section
      1Section.php#?
          ClearShow all
          Date ↕MethodURLData
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